Activating Compound | Comment | Organism | Structure |
---|---|---|---|
apolipoprotein A-I | glycation affects the structure of apoA-I and its ability to activate the enzyme | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
glycated discoidal (A-I)rHDL | after modification of lipid-free apoA-I arginine, lysine and tryptophan residues by glucose | Homo sapiens | |
unesterified cholesterol-(apo lipoprotein A-I-)HDL | the unesterified cholesterol is deuterium-labeled | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
extracellular | - |
Homo sapiens | - |
- |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | key enzyme in reverse cholesterol transport | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
native enzyme from plasma to homogeneity | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
plasma | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | key enzyme in reverse cholesterol transport | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
LCAT | - |
Homo sapiens |
lecithin:cholesterol acyltransferase | - |
Homo sapiens |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Homo sapiens |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | inhibition kinetics | Homo sapiens |