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Literature summary for 2.3.1.5 extracted from

  • Pluvinage, B.; de la Sierra-Gallay, I.L.; Martins, M.; Ragunathan, N.; Dupret, J.M.; Rodrigues-Lima, F.
    Crystallization and preliminary X-ray characterization of arylamine N-acetyltransferase C (BanatC) from Bacillus anthracis (2007), Acta Crystallogr. Sect. F, 63, 862-864.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.3.1.5

Application

Application Comment Organism
pharmacology NATs play an important role in the detoxication and, or bioactivation of numerous drugs and xenobiotics Bacillus anthracis

Cloned(Commentary)

Cloned (Comment) Organism
into the pET28a vector for expression in Escherichia coli BL21DE3 cells Bacillus anthracis

Crystallization (Commentary)

Crystallization (Comment) Organism
crystals diffract to 1.95 A resolution on a synchrotron source Bacillus anthracis

Protein Variants

Protein Variants Comment Organism
Y38F whereas wild-type BanatC proves difficult to crystallize, the mutant displaying the same enzymatic characterisics as the wild-type is found to crystallize and to diffract Bacillus anthracis

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
34000
-
 determined by SDS-PAGE and Western Blot analysis Bacillus anthracis

Organism

Organism UniProt Comment Textmining
Bacillus anthracis
-
-
-

Purification (Commentary)

Purification (Comment) Organism
using HIS-select nickel resin Bacillus anthracis

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetyl-CoA + sulfamethoxazole
-
 Bacillus anthracis ?
-
 ?

Synonyms

Synonyms Comment Organism
arylamine N-acetyltransferase C
-
 Bacillus anthracis
BanatC
-
 Bacillus anthracis
N-hydroxyarylamine O-acetyltransferase
-
 Bacillus anthracis
NAT
-
 Bacillus anthracis