Application | Comment | Organism |
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medicine | co-expression of Escherichia coli nitroreductase and arylamine N-acetyltransferase NAT2 in SKOV3 cells decreases the IC50 value of prodrug CB1954, i.e. 5-(aziridin-1-yl)-2,4-dinitrobenzamide, 16fold. The significantly decreased bystander effect may provide a greater clinical response at therapeutic concentrations of CB1954 | Homo sapiens |
Organism | UniProt | Comment | Textmining |
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Homo sapiens | - |
- |
- |