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Literature summary for 2.3.1.6 extracted from

  • Gabrielle, P.; Jeana, M.; Lorenza, E.C.
    Cytosolic choline acetyltransferase binds specifically to cholinergic plasma membrane of rat brain synaptosomes to generate membrane-bound enzyme (2003), Neurochem. Res., 28, 543-549.
    View publication on PubMed
Search for more literature for 2.3.1.6

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Rattus norvegicus 5829
-
plasma membrane associated with synaptic vesicles, can be displaced by treatment with urea or alkaline solutions Rattus norvegicus 5886
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
acetyl-CoA + choline Rattus norvegicus synthesis of the neurotransmitter acetylcholine acetylcholine + CoA
-
 r

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Rattus norvegicus
-
cerebellum 33% of activity membrane associated Rattus norvegicus
-
hippocampus 64% of activity membrane associated Rattus norvegicus
-
liver 15% of activity membrane associated Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetyl-CoA + choline
-
 Rattus norvegicus acetylcholine + CoA
-
 r
acetyl-CoA + choline synthesis of the neurotransmitter acetylcholine Rattus norvegicus acetylcholine + CoA
-
 r