Literature summary for 2.3.1.6 extracted from

Bohacek, J.; Bearl, A.M.; Daniel, J.M.
Long-term ovarian hormone deprivation alters the ability of subsequent oestradiol replacement to regulate choline acetyltransferase protein levels in the hippocampus and prefrontal cortex of middle-aged rats (2008), J. Neuroendocrinol., 20, 1023-1027.

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Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
hippocampus	in both young adult and middle-aged animals, oestradiol treatment initiates immediately after ovariectomy significantly increased ChAT levels in the hippocampus but not in the prefrontal cortex compared to cholesterol control treatment. When oestradiol treatment is initiated 5 months after ovariectomy, it fails to significantly increase ChAT levels in the hippocampus, but does so in the prefrontal cortex	Rattus norvegicus	-
prefrontal cortex	in both young adult and middle-aged animals, oestradiol treatment initiates immediately after ovariectomy significantly increased ChAT levels in the hippocampus but not in the prefrontal cortex compared to cholesterol control treatment. When oestradiol treatment is initiated 5 months after ovariectomy, it fails to significantly increase ChAT levels in the hippocampus, but does so in the prefrontal cortex	Rattus norvegicus	-

Synonyms

Synonyms	Comment	Organism
ChAT	-	Rattus norvegicus
choline acetyltransferase	-	Rattus norvegicus

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Release 2023.1 (January 2023)