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Literature summary for 2.3.1.7 extracted from

  • Sharma, S.; Sun, X.; Agarwal, S.; Rafikov, R.; Dasarathy, S.; Kumar, S.; Black, S.
    Role of carnitine acetyl transferase in regulation of nitric oxide signaling in pulmonary arterial endothelial cells (2013), Int. J. Mol. Sci., 14, 255-272.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.3.1.7

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
acyl-CoA + L-carnitine Homo sapiens
-
 CoA + O-acylcarnitine
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
pulmonary artery endothelial cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acyl-CoA + L-carnitine
-
 Homo sapiens CoA + O-acylcarnitine
-
 ?

Synonyms

Synonyms Comment Organism
carnitine acetyl transferase
-
 Homo sapiens
CRAT
-
 Homo sapiens

General Information

General Information Comment Organism
malfunction silencing the CrAT gene disrupts cellular carnitine homeostasis, reduces the expression of mitochondrial superoxide dismutase 2 and results in an increase in oxidative stress within the mitochondrion Homo sapiens