Literature summary for 2.3.1.74 extracted from

Hinderer, W.; Seitz, H.U.
In vitro inhibition of carrot chalcone synthase by 3'-nucleotidase: the role of the 3-phosphate group of malonyl-coenzyme A in flavonoid biosynthesis (1986), Arch. Biochem. Biophys., 246, 217-224.

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Inhibitors

Inhibitors	Comment	Organism	Structure
3'-Nucleotidase	i.e. EC 3.1.3.6 hydrolyzes the phosphate group in the 3'-position of adenosine, a part of the CoA thioester substrates	Daucus carota
malonyl-3'-dephospho-CoA	50% inhibition at 0.003 mM	Daucus carota

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
4-coumaroyl-CoA + 3 malonyl-CoA	Daucus carota	-	naringenin chalcone + 4 CoA + 3 CO2	-	?

Organism

Organism	UniProt	Comment	Textmining
Daucus carota	-	carrot, ssp. sativa	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
cell suspension culture	-	Daucus carota	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
4-coumaroyl-CoA + 3 malonyl-CoA	-	Daucus carota	naringenin chalcone + 4 CoA + 3 CO2	-	?

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Release 2023.1 (January 2023)