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Literature summary for 2.3.1.85 extracted from

  • Kim, K.J.; Kim, H.Y.; Cho, H.K.; Kim, K.H.; Cheong, J.
    The SDF-1alpha/CXCR4 axis induces the expression of fatty acid synthase via sterol regulatory element binding protein-1 activation in cancer cells (2010), Carcinogenesis, 31, 679-686.
    View publication on PubMed
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Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
-

Source Tissue

Source Tissue Comment Organism Textmining
Hep-G2 cell
-
 Homo sapiens
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Huh-7 cell
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 Homo sapiens
-
liver
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 Homo sapiens
-
SK-BR-3 cell
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 Homo sapiens
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Synonyms

Synonyms Comment Organism
FASN
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 Homo sapiens
fatty acid synthase
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 Homo sapiens

Expression

Organism Comment Expression
Homo sapiens the stromal cell-derived factor-1 alpha/CXCR4 axis induces the expression of fatty acid synthase via sterol regulatory element binding protein-1 activation in cancer cells. Sterol regulatory element-binding protein-1 is a major modulator of fatty acid synthase transcription. Also recombinant stromal cell-derived factor-1 alpha-induced phosphatidylinositol-3'-kinase/protein kinase B (Akt) phosphorylation is involved in the expression or activities of fatty acid synthase up