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Literature summary for 2.3.1.85 extracted from

  • Chen, Q.; Reimer, R.A.
    Dairy protein and leucine alter GLP-1 release and mRNA of genes involved in intestinal lipid metabolism in vitro (2009), Nutrition, 25, 340-349.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
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Source Tissue

Source Tissue Comment Organism Textmining
NCI-H716 cell
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Homo sapiens
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Synonyms

Synonyms Comment Organism
FAS
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Homo sapiens
fatty acid synthase
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Homo sapiens

Expression

Organism Comment Expression
Homo sapiens isoleucine, whey, leucine, valine, skim milk, and casein downregulate the expression of fatty acid synthase in a concentration-dependent manner, a plateau is reached at 1.0% (w/v) skim milk and casein corresponding to about 40% inhibition of FAS expression, whey leads to 54% inhibition of FAS expression at 2.0%(w/v) down