Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.3.1.85 extracted from

  • Wang, Y.; Nie, F.; Ouyang, J.; Wang, X.; Ma, X.
    Inhibitory effects of sea buckthorn procyanidins on fatty acid synthase and MDA-MB-231 cells (2014), Tumour Biol., 35, 9563-9569.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
procyanidin procyanidins isolated from seeds of Hippophae rhamnoides inhibits the activity of FAS and reduces MDA-MB-231 cell viability with an IC50 value of 37.5 microg/ml. Procyanidins induce MDA-MB-231 cell apoptosis Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
MDA-MB-231 cell
-
Homo sapiens
-

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
additional information
-
IC50 value is 0.087 microg/ml, 37°C, pH not specified in the publication Homo sapiens procyanidin