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Literature summary for 2.3.1.87 extracted from

  • De Angelis, J.; Gastel, J.; Klein, D.C.; Cole, P.A.
    Kinetic analysis of the catalytic mechanism of serotonin N-acetyltransferase (EC 2.3.1.87) (1998), J. Biol. Chem., 273, 3045-3050.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
desulfo-CoA dead end inhibitor analog, competitive versus CoA Ovis aries
tryptophol dead end inhibitor analog, competitive versus tryptamine Ovis aries

Organism

Organism UniProt Comment Textmining
Ovis aries
-
glutathione S-transferase fusion protein, fused and cleaved form
-

Reaction

Reaction Comment Organism Reaction ID
acetyl-CoA + a 2-arylethylamine = CoA + an N-acetyl-2-arylethylamine ordered bi-bi sequential mechanism Ovis aries

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetyl-CoA + tryptophol structural analogue to tryptamine Ovis aries CoA + N-acetyltryptophol
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