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Literature summary for 2.3.1.97 extracted from
- Detection of myristoyl CoA:protein N-myristoyltransferase activity by ion-exchange chromatography (1989), Anal. Biochem., 181, 254-258.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| additional information | no inhibition by 10 mM EDTA | Mus musculus |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytosol | - |
Mus musculus | 5829 | - |
| membrane | - |
Mus musculus | 16020 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| myristoyl-CoA + glycylpeptide | Mus musculus | specific for Gly at N-terminus | N-myristoylglycylpeptide + CoA | - |
? |  |
| myristoyl-CoA + glycylpeptide | Mus musculus | diverse protein substrates, protein biosynthesis | N-myristoylglycylpeptide + CoA | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| partially | Mus musculus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | - |
Mus musculus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
assay method | Mus musculus |
Storage Stability
| Storage Stability | Organism |
|---|---|
| -100°C, 20 mM Tris/HCl buffer, pH 7.1, 1 mM EDTA, 1 mM DTT, 25% glycerol | Mus musculus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| myristoyl-CoA + Gly-Asn-Ala-Ala-Ala-Ala-Arg-Arg | - |
Mus musculus | N-myristoyl-Gly-Asn-Ala-Ala-Ala-Ala-Arg-Arg + CoA | - |
? | |
| myristoyl-CoA + glycylpeptide | - |
Mus musculus | N-myristoylglycylpeptide + CoA | - |
? | |
| myristoyl-CoA + glycylpeptide | specific for Gly at N-terminus | Mus musculus | N-myristoylglycylpeptide + CoA | - |
? | |
| myristoyl-CoA + glycylpeptide | diverse protein substrates, protein biosynthesis | Mus musculus | N-myristoylglycylpeptide + CoA | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| NMT | - |
Mus musculus |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 30 | - |
assay at | Mus musculus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.8 | - |
assay at | Mus musculus |
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Release 2023.1 (January 2023)
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