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Literature summary for 2.3.1.97 extracted from
- Expression of myristoyltransferase and its interacting proteins in epilepsy (2005), Biochem. Biophys. Res. Commun., 335, 1132-1139.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | since myristoylation has a central role in virus maturation and oncogenesis, specific NMT inhibitors might lead to potent antivirus and anticancer agents | Homo sapiens |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression in Escherichia coli | Homo sapiens |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| membrane | - |
Rattus norvegicus | 16020 | - |
| membrane | - |
Bos taurus | 16020 | - |
| membrane | - |
Oryctolagus cuniculus | 16020 | - |
| membrane | NMT activity remains associated with the transmembrane fraction even after extensive washings | Homo sapiens | 16020 | - |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 48000 | - |
- |
Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
| Candida sp. (in: Saccharomycetales) | - |
- |
- |
| Dictyostelium sp. | - |
- |
- |
| Homo sapiens | - |
- |
- |
| Mus musculus | - |
- |
- |
| Oryctolagus cuniculus | - |
- |
- |
| Rattus norvegicus | - |
- |
- |
| Saccharomyces cerevisiae | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Homo sapiens |
- |
Rattus norvegicus |
- |
Bos taurus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | - |
Rattus norvegicus | - |
| brain | - |
Bos taurus | - |
| colonic mucosa | - |
Oryctolagus cuniculus | - |
| HEL TIB 180 cell | erythroleukemia cell line | Homo sapiens | - |
| HeLa cell | - |
Homo sapiens | - |
| liver | - |
Mus musculus | - |
| liver | - |
Rattus norvegicus | - |
| spleen | - |
Bos taurus | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| NMT | - |
Mus musculus |
| NMT | - |
Homo sapiens |
| NMT | - |
Rattus norvegicus |
| NMT | - |
Saccharomyces cerevisiae |
| NMT | - |
Bos taurus |
| NMT | - |
Oryctolagus cuniculus |
| NMT | - |
Candida sp. (in: Saccharomycetales) |
| NMT | - |
Dictyostelium sp. |
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Release 2023.1 (January 2023)
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