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Literature summary for 2.3.1.B34 extracted from

  • Xu, J.Y.; You, D.; Leng, P.Q.; Ye, B.C.
    Allosteric regulation of a protein acetyltransferase in Micromonospora aurantiaca by the amino acids cysteine and arginine (2014), J. Biol. Chem., 289, 27034-27045.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.3.1.B34

Activating Compound

Activating Compound Comment Organism Structure
L-arginine stimulates the activity via conformational changes that occur upon binding to the amino acid-binding-domain Micromonospora aurantiaca
L-cysteine stimulates the activity via conformational changes that occur upon binding to the amino acid-binding-domain Micromonospora aurantiaca

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
acetyl-CoA + [Micau_0428]-L-Lys619 Micromonospora aurantiaca substrate is acetyl-CoA synthase Micau_0428. substrate mutant K619 is not acetylated CoA + [Micau_0428]-N6-acetyl-L-Lys619
-
 ?
acetyl-CoA + [Micau_0428]-L-Lys619 Micromonospora aurantiaca ATCC 27029 substrate is acetyl-CoA synthase Micau_0428. substrate mutant K619 is not acetylated CoA + [Micau_0428]-N6-acetyl-L-Lys619
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 ?

Organism

Organism UniProt Comment Textmining
Micromonospora aurantiaca D9SZU3
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-
Micromonospora aurantiaca ATCC 27029 D9SZU3
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-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetyl-CoA + [Micau_0428]-L-Lys619 substrate is acetyl-CoA synthase Micau_0428. substrate mutant K619 is not acetylated Micromonospora aurantiaca CoA + [Micau_0428]-N6-acetyl-L-Lys619
-
 ?
acetyl-CoA + [Micau_0428]-L-Lys619 substrate is acetyl-CoA synthase Micau_0428. substrate mutant K619 is not acetylated Micromonospora aurantiaca ATCC 27029 CoA + [Micau_0428]-N6-acetyl-L-Lys619
-
 ?

Synonyms

Synonyms Comment Organism
GCN5-related N-acetyltransferase
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 Micromonospora aurantiaca
KAT
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 Micromonospora aurantiaca
Micau_1670
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 Micromonospora aurantiaca