Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P62837 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
SW-60 cell | colon carcinoma cell | Homo sapiens | - |
testis | most abundant expression | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
[ubiquitin-activating protein Uba6]-S-ubiquitinyl-L-cysteine + [ubiquitin carrier protein UbcH5B]-L-cysteine | - |
Homo sapiens | [ubiquitin-activating protein Uba]-L-cysteine + [ubiquitin carrier protein UbcH5B]-S-ubiquitinyl-L-cysteine | recombinant E1 enzyme Uba6 can activate ubiquitin and transfer it onto the ubiquitin-conjugating enzyme UbcH5B. Ubiquitin activated by Uba6 can be used for ubiquitylation of p53 and supports the autoubiquitylation of the E3 ubiquitin ligases HectH9 and E6-AP | ? |
Synonyms | Comment | Organism |
---|---|---|
Ubc4 | - |
Homo sapiens |
UbcH5B | - |
Homo sapiens |