KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00083 | - |
[histone H2A]-L-lysine | E2 enzyme of 20 kDa, pH 7.5, 37°C | Oryctolagus cuniculus | |
0.0015 | - |
[histone H2B]-L-lysine | E2 enzyme of 20 kDa, pH 7.5, 37°C | Oryctolagus cuniculus | |
0.0028 | - |
[histone H2A]-L-lysine | E2 enzyme of 32 kDa, pH 7.5, 37°C | Oryctolagus cuniculus | |
0.012 | - |
[histone H2B]-L-lysine | E2 enzyme of 32 kDa, pH 7.5, 37°C | Oryctolagus cuniculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Oryctolagus cuniculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
reticulocyte | - |
Oryctolagus cuniculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [histone H1]-L-lysine | - |
Oryctolagus cuniculus | [E1 ubiquitin-activating enzyme]-L-cysteine + N6-monoubiquitinyl-[histone H1]-L-lysine | significant rates of processive multiple ubiquitination of calf thymus H1 are catalyzed by E2 enzymes of 14 kDa, 20 kDa, and 32 kDa | ? | |
S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [histone H2A]-L-lysine | - |
Oryctolagus cuniculus | [E1 ubiquitin-activating enzyme]-L-cysteine + N6-monoubiquitinyl-[histone H2A]-L-lysine | significant rates of nonprocessive core histone monoubiquitination are catalyzed by E2 enzymes of 14 kDa, 20 kDa, and 32 kDa | ? | |
S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [histone H2B]-L-lysine | - |
Oryctolagus cuniculus | [E1 ubiquitin-activating enzyme]-L-cysteine + N6-monoubiquitinyl-[histone H2B]-L-lysine | significant rates of nonprocessive core histone monoubiquitination are catalyzed by E2 enzymes of 14 kDa, 20 kDa, and 32 kDa | ? | |
S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [histone H3]-L-lysine | - |
Oryctolagus cuniculus | [E1 ubiquitin-activating enzyme]-L-cysteine + N6-monoubiquitinyl-[histone H3]-L-lysine | significant rates of nonprocessive core histone monoubiquitination are catalyzed by E2 enzymes of 14 kDa, 20 kDa, and 32 kDa | ? | |
S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [histone H4]-L-lysine | - |
Oryctolagus cuniculus | [E1 ubiquitin-activating enzyme]-L-cysteine + N6-monoubiquitinyl-[histone H4]-L-lysine | significant rates of nonprocessive core histone monoubiquitination are catalyzed by E2 enzymes of 14 kDa, 20 kDa, and 32 kDa | ? |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.001 | - |
[histone H2A]-L-lysine | E2 enzyme of 20 kDa, pH 7.5, 37°C | Oryctolagus cuniculus | |
0.0013 | - |
[histone H2A]-L-lysine | E2 enzyme of 32 kDa, pH 7.5, 37°C | Oryctolagus cuniculus | |
0.0022 | - |
[histone H2B]-L-lysine | E2 enzyme of 20 kDa, pH 7.5, 37°C | Oryctolagus cuniculus | |
0.0033 | - |
[histone H2B]-L-lysine | E2 enzyme of 32 kDa, pH 7.5, 37°C | Oryctolagus cuniculus |