Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.3.2.B12 extracted from

  • Huang, Y.; Minaker, S.; Roth, C.; Huang, S.; Hieter, P.; Lipka, V.; Wiermer, M.; Li, X.
    An E4 ligase facilitates polyubiquitination of plant immune receptor resistance proteins in Arabidopsis (2014), Plant Cell, 26, 485-496.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.3.2.B12

Protein Variants

Protein Variants Comment Organism
additional information mutations of MUSE3, muse3-1 and muse3-2 show enhanced resistance against the virulent oomycete Hyaloperonospora arabidopsidis Noco2 or the bacterial pathogen Pseudomonas syringae pv maculicola ES4326 Arabidopsis thaliana

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
 Arabidopsis thaliana 5737
-
nucleus
-
 Arabidopsis thaliana 5634
-

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information MUSE3 functions as an E4 factor and works downstream of the E3 ligase SCFCPR1 to facilitate the polyubiquitination and degradation of Resistance proteins, including SNC1 (Supressor of NPR1, Constitutive 1) and RPS2 (Resistance to Pseudomonas syringae 2) Arabidopsis thaliana ?
-
 ?

Synonyms

Synonyms Comment Organism
E4 factor
-
 Arabidopsis thaliana
E4 ligase
-
 Arabidopsis thaliana
E4 ubiquitin ligase
-
 Arabidopsis thaliana
MUSE3 Mutant, snc-1-enhancing 3 Arabidopsis thaliana
Ub-conjugating E4 factor
-
 Arabidopsis thaliana

General Information

General Information Comment Organism
evolution MUSE3 is a single copy gene encoding a ubiquitin-conjugating E4 factor with a conserved Ub-elongating factor core domain (UFD2p core domain) and a C-terminal U-box domain. Phylogenetic analysis shows that MUSE3 is a highly conserved protein in all sequenced eukaryotes Arabidopsis thaliana
physiological function MUSE3 functions as an E4 factor and works downstream of the E3 ligase SCFCPR1 to facilitate the polyubiquitination and degradation of Resistance proteins, including SNC1 (Supressor of NPR1, Constitutive 1) and RPS2 (Resistance to Pseudomonas syringae 2) Arabidopsis thaliana