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Literature summary for 2.3.3.1 extracted from

  • Agostinho, F.R.; Reus, G.Z.; Stringari, R.B.; Ribeiro, K.F.; Ferraro, A.K.; Benedet, J.; Rochi, N.; Scaini, G.; Streck, E.L.; Quevedo, J.
    Treatment with olanzapine, fluoxetine and olanzapine/fluoxetine alters citrate synthase activity in rat brain (2011), Neurosci. Lett., 487, 278-281.
    View publication on PubMed
Search for more literature for 2.3.3.1

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Rattus norvegicus
-
cerebellum
-
 Rattus norvegicus
-
corpus striatum
-
 Rattus norvegicus
-
hippocampus
-
 Rattus norvegicus
-
prefrontal cortex
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetyl-CoA + H2O + oxaloacetate
-
 Rattus norvegicus citrate + CoA
-
 ?

Synonyms

Synonyms Comment Organism
citrate synthase
-
 Rattus norvegicus
EC 4.1.3.7 formerly Rattus norvegicus

Expression

Organism Comment Expression
Rattus norvegicus acute administration of olanzapine inhibits citrate synthase activity in cerebellum and prefrontal cortex down
Rattus norvegicus oanzapine 3 mg/kg and fluoxetine 12.5 mg/kg in combination increase citrate synthase activity in prefrontal cortex, hippocampus and striatum. The chronic administration of olanzapine increases citrate synthase activity in prefrontal cortex, hippocampus and striatum and fluoxetine increases citrate synthase activity in striatum up