Inhibitors | Comment | Organism | Structure |
---|---|---|---|
5,5'-dithiobis(2-nitrobenzoic acid) | enzyme inactivation, lauroyl-CoA or palmitoyl-CoA protects | Talaromyces trachyspermus | |
oxaloacetate | competitive to 2-oxoglutarate | Talaromyces trachyspermus | |
palmitoyl-CoA | partially competitive with lauroyl-CoA | Talaromyces trachyspermus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.001 | - |
lauroyl-CoA | - |
Talaromyces trachyspermus | |
0.75 | - |
2-oxoglutarate | - |
Talaromyces trachyspermus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
43000 | - |
? * 43000, SDS-PAGE | Talaromyces trachyspermus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
dodecanoyl-CoA + H2O + 2-oxoglutarate | Talaromyces trachyspermus | - |
(3S,4S)-3-hydroxytetradecane-1,3,4-tricarboxylate + CoA | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Talaromyces trachyspermus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Talaromyces trachyspermus |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
1.25 | - |
- |
Talaromyces trachyspermus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
decanoyl-CoA + H2O + 2-oxoglutarate | - |
Talaromyces trachyspermus | (3S,4S)-3-hydroxydodecane-1,3,4-tricarboxylate + CoA | - |
? | |
dodecanoyl-CoA + H2O + 2-oxoglutarate | - |
Talaromyces trachyspermus | (3S,4S)-3-hydroxytetradecane-1,3,4-tricarboxylate + CoA | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | ? * 43000, SDS-PAGE | Talaromyces trachyspermus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8.3 | - |
- |
Talaromyces trachyspermus |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
7.3 | 9 | 75% of maximal activity at pH 7.5 and 9 | Talaromyces trachyspermus |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.4 | 0.8 | oxaloacetate | competitive inhibitor | Talaromyces trachyspermus |