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Literature summary for 2.3.3.8 extracted from

  • Tajima, A.; Murai, N.; Murakami, Y.; Iwamoto, T.; Migita, T.; Matsufuji, S.
    Polyamine regulating protein antizyme binds to ATP citrate lyase to accelerate acetyl-CoA production in cancer cells (2016), Biochem. Biophys. Res. Commun., 471, 646-651.
    View publication on PubMed
Search for more literature for 2.3.3.8

Activating Compound

Activating Compound Comment Organism Structure
antizyme antizyme 1 and 2 activate the enzyme through protein-protein interaction Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
expressed in 293-F cells Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Homo sapiens 5829
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ADP + phosphate + acetyl-CoA + oxaloacetate Homo sapiens
-
 ATP + citrate + CoA
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
A-549 cell
-
 Homo sapiens
-
LNCaP cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ADP + phosphate + acetyl-CoA + oxaloacetate
-
 Homo sapiens ATP + citrate + CoA
-
 ?

Synonyms

Synonyms Comment Organism
ACLY
-
 Homo sapiens
ATP citrate lyase
-
 Homo sapiens