Organism | UniProt | Comment | Textmining |
---|---|---|---|
Caenorhabditis elegans | - |
- |
- |
Drosophila melanogaster | - |
- |
- |
Mus musculus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
UDP-N-acetyl-D-glucosamine + Manalpha(1-3)Manalpha(1-6)[Manalpha(1-3)]Manbeta(1-4)GlcNAcbeta(1-4)GlcNAc-R | - |
Drosophila melanogaster | UDP + Manalpha(1-3)Manalpha(1-6)[GlcNAcbeta(1-2)Manalpha(1-3)]Manbeta(1-4)GlcNAcbeta(1-4)GlcNAc-R | - |
? | |
UDP-N-acetyl-D-glucosamine + Manalpha(1-3)Manalpha(1-6)[Manalpha(1-3)]Manbeta(1-4)GlcNAcbeta(1-4)GlcNAc-R | - |
Mus musculus | UDP + Manalpha(1-3)Manalpha(1-6)[GlcNAcbeta(1-2)Manalpha(1-3)]Manbeta(1-4)GlcNAcbeta(1-4)GlcNAc-R | - |
? | |
UDP-N-acetyl-D-glucosamine + Manalpha(1-3)Manalpha(1-6)[Manalpha(1-3)]Manbeta(1-4)GlcNAcbeta(1-4)GlcNAc-R | - |
Caenorhabditis elegans | UDP + Manalpha(1-3)Manalpha(1-6)[GlcNAcbeta(1-2)Manalpha(1-3)]Manbeta(1-4)GlcNAcbeta(1-4)GlcNAc-R | - |
? | |
UDP-N-acetyl-D-glucosamine + Manalpha(1-6)[Manalpha(1-3)]Manalpha(1-6)[Manalpha(1-3)]Manbeta(1-4)GlcNAcbeta(1-4)GlcNAc-R | - |
Drosophila melanogaster | UDP + Manalpha(1-6)[Manalpha(1-3)]Manalpha(1-6)[GlcNAcbeta(1-2)Manalpha(1-3)]Manbeta(1-4)GlcNAcbeta(1-4)GlcNAc-R | - |
? | |
UDP-N-acetyl-D-glucosamine + Manalpha(1-6)[Manalpha(1-3)]Manalpha(1-6)[Manalpha(1-3)]Manbeta(1-4)GlcNAcbeta(1-4)GlcNAc-R | - |
Mus musculus | UDP + Manalpha(1-6)[Manalpha(1-3)]Manalpha(1-6)[GlcNAcbeta(1-2)Manalpha(1-3)]Manbeta(1-4)GlcNAcbeta(1-4)GlcNAc-R | - |
? | |
UDP-N-acetyl-D-glucosamine + Manalpha(1-6)[Manalpha(1-3)]Manalpha(1-6)[Manalpha(1-3)]Manbeta(1-4)GlcNAcbeta(1-4)GlcNAc-R | - |
Caenorhabditis elegans | UDP + Manalpha(1-6)[Manalpha(1-3)]Manalpha(1-6)[GlcNAcbeta(1-2)Manalpha(1-3)]Manbeta(1-4)GlcNAcbeta(1-4)GlcNAc-R | - |
? | |
UDP-N-acetyl-D-glucosamine + Manalpha(1-6)[Manalpha(1-3)]Manbeta(1-4)GlcNAcbeta(1-4)GlcNAc-R | - |
Drosophila melanogaster | UDP + Manalpha(1-6)[GlcNAcbeta(1-2)Manalpha(1-3)]Manbeta(1-4)GlcNAcbeta(1-4)GlcNAc-R | - |
? | |
UDP-N-acetyl-D-glucosamine + Manalpha(1-6)[Manalpha(1-3)]Manbeta(1-4)GlcNAcbeta(1-4)GlcNAc-R | - |
Mus musculus | UDP + Manalpha(1-6)[GlcNAcbeta(1-2)Manalpha(1-3)]Manbeta(1-4)GlcNAcbeta(1-4)GlcNAc-R | - |
? | |
UDP-N-acetyl-D-glucosamine + Manalpha(1-6)[Manalpha(1-3)]Manbeta(1-4)GlcNAcbeta(1-4)GlcNAc-R | - |
Caenorhabditis elegans | UDP + Manalpha(1-6)[GlcNAcbeta(1-2)Manalpha(1-3)]Manbeta(1-4)GlcNAcbeta(1-4)GlcNAc-R | - |
? |
Synonyms | Comment | Organism |
---|---|---|
gly-12 | - |
Caenorhabditis elegans |
GLY-13 | - |
Caenorhabditis elegans |
gly-14 | - |
Caenorhabditis elegans |
GnTI | - |
Drosophila melanogaster |
GnTI | - |
Mus musculus |
GnTI | - |
Caenorhabditis elegans |
MGAT1 | - |
Drosophila melanogaster |
MGAT1 | - |
Mus musculus |
MGAT1 | - |
Caenorhabditis elegans |
UDP-GlcNAc:alpha3-D-mannoside beta1,2-N-acetylglucosaminyltransferase I | - |
Drosophila melanogaster |
UDP-GlcNAc:alpha3-D-mannoside beta1,2-N-acetylglucosaminyltransferase I | - |
Mus musculus |
UDP-GlcNAc:alpha3-D-mannoside beta1,2-N-acetylglucosaminyltransferase I | - |
Caenorhabditis elegans |
General Information | Comment | Organism |
---|---|---|
malfunction | Mgat1-null flies are viable but exhibit pronounced defects in locomotion. Neuron-specific RNAi knockdown of Mgat1 in wild-type flies results in locomotory defects, reduced life span, and about 50% reduction in enzyme activity | Drosophila melanogaster |
malfunction | Mgat1-null mouse embryos die at 9.5-10.5 days after fertilization | Mus musculus |
malfunction | worms with either deletion or RNA-mediated down-regulation of the gly-14 gene are completely resistant to killing by bacteria on PGS medium | Caenorhabditis elegans |
physiological function | Mgat1-dependent N-glycans are required for normal development | Drosophila melanogaster |
physiological function | Mgat1-dependent N-glycans are required for normal development | Mus musculus |
physiological function | Mgat1-dependent N-glycans are required for normal development | Caenorhabditis elegans |