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Literature summary for 2.4.1.102 extracted from
- Regulation of UDP-GlcNAc:Galbeta1-3GalNAc-R beta1-6-N-acetylglucosaminyltransferase (GlcNAc to GalNAc) in chinese hamster ovary cells (1993), J. Biol. Chem., 268, 5409-5416.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| additional information | no effect of dimethyl sulfoxide, retinoic acid, phorbol ester, cholera toxin | Cricetulus griseus | |
| sodium butyrate | induction after treatment of cells for 24 h, 16fold increase in activity, blocked by actinomycin D and cycloheximide | Cricetulus griseus |  |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| additional information | no effect of dimethyl sulfoxide, retinoic acid, phorbol ester, cholera toxin | Cricetulus griseus |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.5 | - |
UDP-N-acetyl-D-glucosamine | - |
Cricetulus griseus | |
| 4.54 | - |
UDP-N-acetyl-D-glucosamine | butyrate treated cells | Cricetulus griseus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Cricetulus griseus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| CHO cell | - |
Cricetulus griseus | - |
| ovary | - |
Cricetulus griseus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-1,3-N-acetyl-D-galactosaminyl-R | - |
Cricetulus griseus | UDP + beta-D-galactosyl-1,3-(N-acetyl-beta-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl-R | i.e. core class 2 | ? | |
| UDP-N-acetyl-D-glucosamine + galactosyl-beta-1,3-N-acetyl-beta-D-glucosaminyl-p-nitrophenyl | - |
Cricetulus griseus | UDP + galactosyl-beta-1,3-(N-acetyl-beta-D-glucosaminyl-1,6)-N-acetyl-beta-D-glucosaminyl-p-nitrophenyl | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| core 2 GlcNAc-T | - |
Cricetulus griseus |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
assay at | Cricetulus griseus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.4 | - |
assay at | Cricetulus griseus |
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Release 2023.1 (January 2023)
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