Literature summary for 2.4.1.102 extracted from

Julien, S.; Grimshaw, M.J.; Sutton-Smith, M.; Coleman, J.; Morris, H.R.; Dell, A.; Taylor-Papadimitriou, J.; Burchell, J.M.
Sialyl-Lewis(x) on P-selectin glycoprotein ligand-1 is regulated during differentiation and maturation of dendritic cells: a mechanism involving the glycosyltransferases C2GnT1 and ST3Gal I (2007), J. Immunol., 179, 5701-5710.

Search for more literature for 2.4.1.102

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
dendritic cell	maturation of dendritic cells leads to a rapid change in the expression of glycosyltransferases involved in O-linked glycosylation. A down-regulation of C2GnT1 mRNA and enzymatic activity is observed with a concurrent up-regulation of ST3Gal I and ST6GalNAc II mRNA resulting in a loss of the core 2 structures required for sLex expression as a P-selectin ligand	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
C2GnT1	-	Homo sapiens

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)