Application | Comment | Organism |
---|---|---|
diagnostics | detection of core2 beta-1,6-N-acetylglucosaminyltransferase in post-digital rectal examination urine is a reliable indicator for extracapsular extension of prostate cancer. The number of GCNT1-positive cases is significantly lower in cases of organ-confined disease than in cases of extracapsular extension. GCNT1-negative tumors are a associated with significantly better prostate-specific antigen (PSA)-free survival compared with GCNT1-positive tumors. Multivariate analysis reveals that detection of GCNT1 expression is an independent risk factor for prostate-specific antigen recurrence | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
prostate cancer cell | GCNT1 immunohistochemic analysis, overview. The anti-GCNT1 monoclonal antibody shows high specificity against human GCNT1 | Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
core2 beta-1,6-N-acetylglucosaminyltransferase | - |
Homo sapiens |
core2 beta-1,6-N-acetylglucosaminyltransferase-1 | - |
Homo sapiens |
GCNT1 | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | enzyme GCNT1 expression in prostate cancer specimens from radical prostatectomy correlates with prostate cancer aggressiveness | Homo sapiens |