Literature summary for 2.4.1.109 extracted from

Lommel, M.; Willer, T.; Strahl, S.
POMT2, a key enzyme in Walker-Warburg syndrome: somatic sPOMT2, but not testis-specific tPOMT2, is crucial for mannosyltransferase activity in vivo (2008), Glycobiology, 18, 615-625.

Search for more literature for 2.4.1.109

Organism

Organism	UniProt	Comment	Textmining
Bos taurus	-	-	-
Canis lupus familiaris	-	-	-
Equus caballus	-	-	-
Felis catus	-	-	-
Mus musculus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
embryo	sPomt2, but not tPomt2, is prominently expressed in mouse embryos in the tissues that are most severely affected in Walker-Warburg syndrome (developing muscle, eye, and brain)	Mus musculus	-
germ cell	tPOMT2 is restricted to the acrosome of male germ cells and is not involved in the biosynthesis of O-mannosyl glycans in vivo. tPOMT2 is highly conserved among mammals, including humans, suggesting a crucial function that is distinct from sPOMT2	Mus musculus	-
testis	in testis both POMT2 isoforms are stably expressed. In contrast to tPOMT2, which is restricted to developing spermatogenic cells, sPOMT2 is present in nonspermatogenic cells. sPOMT2POMT1 complexes catalyze mannosyltransfer in adult somatic tissues and testis	Mus musculus	-

Synonyms

Synonyms	Comment	Organism
POMT2	-	Bos taurus
POMT2	-	Canis lupus familiaris
POMT2	-	Felis catus
POMT2	-	Equus caballus
protein mannosyltransferase	-	Mus musculus
sPOMT2	-	Mus musculus
tPOmt2	-	Mus musculus

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Release 2023.1 (January 2023)