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BRENDA support

Literature summary for 2.4.1.110 extracted from

  • Okada, N.; Nishimura, S.
    Enzymatic synthesis of Q nucleoside containing mannose in the anticodon of tRNA: isolation of a novel mannosyltransferase from a cell-free extract of rat liver (1977), Nucleic Acids Res., 4, 2931-2937.
    View publication on PubMedView publication on EuropePMC

Inhibitors

Inhibitors Comment Organism Structure
EDTA
-
Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
soluble
-
Rattus norvegicus
-
-

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ requirement Rattus norvegicus
NaCl 0.1 M NaCl stimulates more than 2fold Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
GDP-alpha-D-mannose + queuosine34 in tRNAAsp Rattus norvegicus
-
GDP + O-4''-alpha-D-mannosylqueuosine34 in tRNAAsp
-
?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
male Donryu
-

Purification (Commentary)

Purification (Comment) Organism
partial Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GDP-alpha-D-mannose + queuosine34 in tRNAAsp
-
Rattus norvegicus GDP + O-4''-alpha-D-mannosylqueuosine34 in tRNAAsp
-
?
GDP-alpha-D-mannose + queuosine34 in tRNAAsp strict specificity for E. coli tRNAAsp, transfer with concomitant inversion of anomeric configuration at sugar C-1-carbon, no substrates are tRNATyr, tRNAHis or tRNAAsn Rattus norvegicus GDP + O-4''-alpha-D-mannosylqueuosine34 in tRNAAsp
-
?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
-
Rattus norvegicus