Cloned (Comment) | Organism |
---|---|
CesA2, expression in Escherichia coli strain BL21(DE3) and in human U2OS osteosarcoma cells as GFP-tagged enzyme using the pCDNA6.2/GW/C-EmGFP vector | Saprolegnia monoica |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
actin filament | - |
Saprolegnia monoica | 5884 | - |
cytoplasm | co-localized with F-actin | Saprolegnia monoica | 5737 | - |
additional information | CesA2 might co-localize with microtubules in vivo | Saprolegnia monoica | - |
- |
nucleolus | co-localized with F-actin | Saprolegnia monoica | 5730 | - |
nucleoplasm | co-localized with F-actin | Saprolegnia monoica | 5654 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Saprolegnia monoica | CesA2 binds in vitro to phosphoinositides, F-actin and microtubules via its PH domain, and co-localizes with F-actin in vivo | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saprolegnia monoica | C9WPJ9 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | CesA2 binds in vitro to phosphoinositides, F-actin and microtubules via its PH domain, and co-localizes with F-actin in vivo | Saprolegnia monoica | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
cellulose synthase 2 | - |
Saprolegnia monoica |
CesA2 | - |
Saprolegnia monoica |
General Information | Comment | Organism |
---|---|---|
evolution | SmCesA2PH shares the PPBM motif with several PH domains of human proteins, the SmCesA2 PH domain is similar to the C-terminal PH domain of the human protein TAPP1 | Saprolegnia monoica |
physiological function | the SmCesA2 PH domain binds in vitro to phosphoinositides, F-actin and microtubules, and co-localizes with F-actin in vivo. The SmCesA2 PH domain has a role in the regulation, trafficking and/or targeting of the cell wall synthesizing enzyme | Saprolegnia monoica |