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Literature summary for 2.4.1.129 extracted from

  • Park, W.; Seto, H.; Hakenbeck, R.; Matsuhashi, M.
    Major peptidoglycan transglycosylase activity in Streptococcus pneumoniae that is not a penicillin-binding protein (1985), FEMS Microbiol. Lett., 27, 45-48.
No PubMed abstract available
Search for more literature for 2.4.1.129

Activating Compound

Activating Compound Comment Organism Structure
Triton X-100
-
 Escherichia coli
Triton X-100 up to 0.6% Streptococcus pneumoniae

Inhibitors

Inhibitors Comment Organism Structure
Moenomycin
-
 Escherichia coli
Moenomycin
-
 Streptococcus pneumoniae
Triton X-100 up to 0.6% Streptococcus pneumoniae
Vancomycin
-
 Escherichia coli
Vancomycin
-
 Streptococcus pneumoniae

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Escherichia coli 16020
-
membrane
-
 Streptococcus pneumoniae 16020
-

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-
Streptococcus pneumoniae
-
-
-
Streptococcus pneumoniae R6cwl
-
-
-

Purification (Commentary)

Purification (Comment) Organism
partial Streptococcus pneumoniae

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme possesses peptidoglycan transglycosylase activity that lacks penicillin-binding activity Streptococcus pneumoniae ?
-
 ?
additional information the enzyme shows both transglycosylase and transpeptidase activities Escherichia coli ?
-
 ?
additional information the enzyme possesses peptidoglycan transglycosylase activity that lacks penicillin-binding activity Streptococcus pneumoniae R6cwl ?
-
 ?
[GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n-diphosphoundecaprenol + GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol
-
 Escherichia coli [GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n+1-diphosphoundecaprenol + undecaprenyl diphosphate
-
 ?
[GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n-diphosphoundecaprenol + GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol
-
 Streptococcus pneumoniae [GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n+1-diphosphoundecaprenol + undecaprenyl diphosphate
-
 ?
[GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n-diphosphoundecaprenol + GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol
-
 Streptococcus pneumoniae R6cwl [GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n+1-diphosphoundecaprenol + undecaprenyl diphosphate
-
 ?