Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(2R,3'R)-3-(3-O-(2-acetamido-2-deoxy-beta-D-glucopyranosyl)propylphosphinato)-2-(3',7'-dimethyloctyloxy)propanoic acid | 0.1 mM, 25% inhibition, 0.2 mM, 37% inhibition | Escherichia coli | |
(2R,3'R)-3-[3-O-(2-acetamido-2-deoxy-beta-D-glucopyranosyl)propylphosphinato]-2-(3',7'-dimethyloctyloxy)propanoic acid | 0.1 mM., 25% inhibition, 0.2 mM, 61% inhibition | Escherichia coli | |
(R)-3-((2-acetamido-2-deoxy-beta-D-glucopyranosyl-(1-4)-alpha-D-glucopyranosyl)methylphosphinato)-2-octyloxypropanoic acid | 0.1 mM, 17% inhibition | Escherichia coli | |
(R)-3-[3-O-(2-acetamido-2-deoxy-beta-D-glucopyranosyl-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosyl)propylphosphinato]-2-octyloxypropanoic acid | 0.1 mM, 10% inhibition | Escherichia coli | |
(Z)-2-(2-acetamido-2-deoxy-alpha-D-glucopyranosyl)oxymethyl-3-tetradecylbutenedioic acid dilithium salt | 0.1 mM, 28% inhibition | Escherichia coli | |
(Z)-2-farnesyl-3-methylbutenedioic acid dilithium salt | weak inhibition | Escherichia coli | |
(Z)-2-geranyl-3-methylbutenedioic acid dilithium salt | 0.1 mM, 12% inhibition | Escherichia coli | |
(Z)-2-nerolyl-3-methylbutenedioic acid dilithium salt | 0.1 mM, 17% inhibition | Escherichia coli | |
chaetomellic acid A dilithium salt | weak inhibition | Escherichia coli |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Escherichia coli | penicillin-binding protein 1b is the key enzyme responsible for the formation of the polysaccharide backbone of the peptidoglycan as well as for cross-linking of its peptide portion | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | penicillin-binding protein 1b is the key enzyme responsible for the formation of the polysaccharide backbone of the peptidoglycan as well as for cross-linking of its peptide portion | Escherichia coli | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PBP1b | - |
Escherichia coli |
penicillin-binding protein 1B | - |
Escherichia coli |