Literature summary for 2.4.1.129 extracted from

Lovering, A.L.; Gretes, M.; Strynadka, N.C.
Structural details of the glycosyltransferase step of peptidoglycan assembly (2008), Curr. Opin. Struct. Biol., 18, 534-543.

Search for more literature for 2.4.1.129

Activating Compound

Activating Compound	Comment	Organism	Structure
RodA	RodA is required for isoform PBP2 activity	Escherichia coli

Crystallization (Commentary)

Crystallization (Comment)	Organism
-	Staphylococcus aureus
-	Escherichia coli
-	Aquifex aeolicus

Inhibitors

Inhibitors	Comment	Organism
AC326-alpha	-	Aquifex aeolicus
AC326-alpha	-	Bacillus subtilis
AC326-alpha	-	Caulobacter vibrioides
AC326-alpha	-	Cereibacter sphaeroides
AC326-alpha	-	Escherichia coli
AC326-alpha	-	Mycobacterium tuberculosis
AC326-alpha	-	Staphylococcus aureus
ACL19273	-	Aquifex aeolicus
ACL19273	-	Bacillus subtilis
ACL19273	-	Caulobacter vibrioides
ACL19273	-	Cereibacter sphaeroides
ACL19273	-	Escherichia coli
ACL19273	-	Mycobacterium tuberculosis
ACL19273	-	Staphylococcus aureus
Garneau-5	-	Aquifex aeolicus
Garneau-5	-	Bacillus subtilis
Garneau-5	-	Caulobacter vibrioides
Garneau-5	-	Cereibacter sphaeroides
Garneau-5	-	Escherichia coli
Garneau-5	-	Mycobacterium tuberculosis
Garneau-5	-	Staphylococcus aureus
HTS6	-	Aquifex aeolicus
HTS6	-	Bacillus subtilis
HTS6	-	Caulobacter vibrioides
HTS6	-	Cereibacter sphaeroides
HTS6	-	Escherichia coli
HTS6	-	Mycobacterium tuberculosis
HTS6	-	Staphylococcus aureus
HTS7	-	Aquifex aeolicus
HTS7	-	Bacillus subtilis
HTS7	-	Caulobacter vibrioides
HTS7	-	Cereibacter sphaeroides
HTS7	-	Escherichia coli
HTS7	-	Mycobacterium tuberculosis
HTS7	-	Staphylococcus aureus
HTS8	-	Aquifex aeolicus
HTS8	-	Bacillus subtilis
HTS8	-	Caulobacter vibrioides
HTS8	-	Cereibacter sphaeroides
HTS8	-	Escherichia coli
HTS8	-	Mycobacterium tuberculosis
HTS8	-	Staphylococcus aureus
moenomycin A	-	Aquifex aeolicus
moenomycin A	-	Bacillus subtilis
moenomycin A	-	Caulobacter vibrioides
moenomycin A	-	Cereibacter sphaeroides
moenomycin A	-	Escherichia coli
moenomycin A	-	Mycobacterium tuberculosis
moenomycin A	-	Staphylococcus aureus
TS30153	-	Aquifex aeolicus
TS30153	-	Bacillus subtilis
TS30153	-	Caulobacter vibrioides
TS30153	-	Cereibacter sphaeroides
TS30153	-	Escherichia coli
TS30153	-	Mycobacterium tuberculosis
TS30153	-	Staphylococcus aureus

Organism

Organism	UniProt	Comment	Textmining
Aquifex aeolicus	-	-	-
Bacillus subtilis	-	-	-
Caulobacter vibrioides	-	-	-
Cereibacter sphaeroides	-	-	-
Escherichia coli	-	-	-
Mycobacterium tuberculosis	-	-	-
Staphylococcus aureus	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.
[GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n-diphosphoundecaprenol + GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol	-	Staphylococcus aureus	[GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n+1-diphosphoundecaprenol + undecaprenyl diphosphate	-	?
[GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n-diphosphoundecaprenol + GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol	-	Bacillus subtilis	[GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n+1-diphosphoundecaprenol + undecaprenyl diphosphate	-	?
[GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n-diphosphoundecaprenol + GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol	-	Escherichia coli	[GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n+1-diphosphoundecaprenol + undecaprenyl diphosphate	-	?
[GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n-diphosphoundecaprenol + GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol	-	Cereibacter sphaeroides	[GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n+1-diphosphoundecaprenol + undecaprenyl diphosphate	-	?
[GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n-diphosphoundecaprenol + GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol	-	Mycobacterium tuberculosis	[GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n+1-diphosphoundecaprenol + undecaprenyl diphosphate	-	?
[GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n-diphosphoundecaprenol + GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol	-	Caulobacter vibrioides	[GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n+1-diphosphoundecaprenol + undecaprenyl diphosphate	-	?
[GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n-diphosphoundecaprenol + GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol	-	Aquifex aeolicus	[GlcNAc-(1-4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n+1-diphosphoundecaprenol + undecaprenyl diphosphate	-	?

Synonyms

Synonyms	Comment	Organism
PBP1	isoform	Bacillus subtilis
PBP1a	-	Aquifex aeolicus
PBP1a	isoform	Escherichia coli
PBP1a	isoform	Caulobacter vibrioides
PBP1b	isoform	Escherichia coli
PBP2	-	Staphylococcus aureus
PBP2	isoform	Escherichia coli
PBP2	isoform	Cereibacter sphaeroides
PBP2	isoform	Caulobacter vibrioides
PBP2A	isoform	Bacillus subtilis
PBP2A	isoform	Caulobacter vibrioides
PBP2b	isoform	Caulobacter vibrioides
PBP2c	isoform	Bacillus subtilis
PBP2d	isoform	Bacillus subtilis
PBP3	isoform	Bacillus subtilis
PBP3	isoform	Escherichia coli
PBP4	isoform	Bacillus subtilis
PBP7	isoform	Escherichia coli
PBP8	isoform	Escherichia coli
PBPA	isoform	Mycobacterium tuberculosis

General Information

General Information	Comment	Organism
physiological function	isoform PBP3 is required for localization of MurG to division site	Escherichia coli