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Literature summary for 2.4.1.135 extracted from

  • Wei, G.; Bai, X.; Sarkar, A.K.; Esko, J.D.
    Formation of HNK-1 determinants and the glycosaminoglycan tetrasaccharide linkage region by UDP-GlcUA:galactose beta1,3-glucuronosyltransferases (1999), J. Biol. Chem., 274, 7857-7864.
    View publication on PubMed
Search for more literature for 2.4.1.135

Cloned(Commentary)

Cloned (Comment) Organism
transfection of a CHO cell mutant defective in GlcUAT-I with the hamster cDAN restores glycosaminoglycan assembly in vivo Cricetulus griseus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.67
-
 Galbeta1,3Galbeta-O-naphthalenemethanol pH 6.5, 37°C Cricetulus griseus
1.8
-
 Galbeta1,4GlcNAcbeta-O-naphthalenemethanol pH 6.5, 37°C Cricetulus griseus
2.9
-
 Galbeta1,3GlcNAcbeta-O-naphthalenemethanol pH 6.5, 37°C Cricetulus griseus
3.2
-
 Galbeta1,3GalNAcbeta-O-naphthalenemethanol pH 6.5, 37°C Cricetulus griseus

Organism

Organism UniProt Comment Textmining
Cricetulus griseus Q9WU47
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Cricetulus griseus
-
CHO cell
-
 Cricetulus griseus
-
heart
-
 Cricetulus griseus
-
kidney
-
 Cricetulus griseus
-
liver
-
 Cricetulus griseus
-
lung
-
 Cricetulus griseus
-
additional information barely detectable in spleen Cricetulus griseus
-
skeletal muscle
-
 Cricetulus griseus
-
testis
-
 Cricetulus griseus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information no activity with Galalpha-O-p-nitrophenol, Galbeta-O-p-nitrophenol, Galalpha-O-a-naphthol, GalNAcalpha-O-p-nitrophenol, GalNAcbeta-O-p-nitrophenol Cricetulus griseus ?
-
 ?
UDP-alpha-D-glucuronate + Galbeta1,3Galbeta-O-naphthalenemethanol
-
 Cricetulus griseus ?
-
 ?
UDP-alpha-D-glucuronate + Galbeta1,3GalNAcbeta-O-naphthalenemethanol
-
 Cricetulus griseus ?
-
 ?
UDP-glucuronate + Galbeta(1-3)Gal-O-benzyl best substrate Cricetulus griseus UDP + ?
-
 ?
UDP-glucuronate + Galbeta(1-3)Gal-O-naphthalenemethanol best substrate Cricetulus griseus UDP + ?
-
 ?
UDP-glucuronate + Galbeta(1-3)GlcNAcalpha-O-benzyl
-
 Cricetulus griseus UDP + ?
-
 ?
UDP-glucuronate + Galbeta(1-3)GlcNAcalpha-O-naphthalenemethanol
-
 Cricetulus griseus UDP + ?
-
 ?
UDP-glucuronate + Galbeta(1-3)GlcNAcbeta-O-naphthalenemethanol
-
 Cricetulus griseus UDP + ?
-
 ?
UDP-glucuronate + Galbeta(1-4)Glcbeta-O-naphthalenemethanol
-
 Cricetulus griseus UDP + ?
-
 ?
UDP-glucuronate + Galbeta(1-4)GlcNAcbeta-O-naphthalenemethanol
-
 Cricetulus griseus UDP + ?
-
 ?
UDP-glucuronate + Galbeta-O-1-naphthol
-
 Cricetulus griseus UDP + GlcAbeta(1-3)Galbeta-O-1-naphthol
-
 ?
UDP-glucuronate + Galbeta-O-2-naphthol
-
 Cricetulus griseus UDP + GlcAbeta(1-3)Galbeta-O-2-naphthol
-
 ?

Synonyms

Synonyms Comment Organism
GlcUAT-I
-
 Cricetulus griseus