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Literature summary for 2.4.1.141 extracted from

  • Kean, E.L.; Niu, N.
    Kinetics of formation of GlcNAc-GlcNAc-P-P-dolichol by microsomes from the retina of the embryonic chick (1998), Glycoconjugate J., 15, 11-17.
    View publication on PubMed
Search for more literature for 2.4.1.141

Activating Compound

Activating Compound Comment Organism Structure
TX-100 0.15% Gallus gallus

Inhibitors

Inhibitors Comment Organism Structure
Amphomycin partial inhibition Gallus gallus
Diumycin
-
 Gallus gallus
EDTA
-
 Gallus gallus
Mg2+ concentrations above 6.7 mM Gallus gallus
Showdomycin complete inhibition Gallus gallus
UDP
-
 Gallus gallus
UDPglucose
-
 Gallus gallus
UMP
-
 Gallus gallus
UTP
-
 Gallus gallus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.00264
-
 N-acetyl-D-glucosaminyl-diphosphodolichol
-
 Gallus gallus
0.0571
-
 UDP-N-acetyl-D-glucosamine
-
 Gallus gallus

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
 Gallus gallus
-
-

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ slight enhancement in activity at 6.7 mM Gallus gallus
Mn2+ stimulates, not as effective as Mg2+ Gallus gallus

Organism

Organism UniProt Comment Textmining
Gallus gallus
-
 15-16 days old
-

Source Tissue

Source Tissue Comment Organism Textmining
retina
-
 Gallus gallus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-N-acetyl-alpha-D-glucosamine + N-acetyl-alpha-D-glucosaminyl-diphosphodolichol
-
 Gallus gallus UDP + N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphosphodolichol
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Gallus gallus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
-
 Gallus gallus