Literature summary for 2.4.1.148 extracted from

Vanderplasschen, A.; Markine-Goriaynoff, N.; Lomonte, P.; Suzuki, M.; Hiraoka, N.; Yeh, J.C.; Bureau, F.; Willems, L.; Thiry, E.; Fukuda, M.; Pastoret, P.P.
A multipotential beta-1,6-N-acetylglucosaminyltransferase is encoded by bovine herpesvirus type 4 (2000), Proc. Natl. Acad. Sci. USA, 97, 5756-5761.

Search for more literature for 2.4.1.148

Cloned(Commentary)

Cloned (Comment)	Organism
functional expression in CHO cells, soluble chimeric enzyme form shows core 4 6beta-GalNAc transferase activity, DNA and amino acid sequence determination	Bovine gammaherpesvirus 4

Organism

Organism	UniProt	Comment	Textmining
Bovine gammaherpesvirus 4	Q9IZK2	i.e. BHV-4	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
UDP-N-acetyl-D-glucosamine + N-acetyl-beta-D-glucosaminyl-1,3-N-acetyl-alpha-D-galactosaminyl-p-nitrophenol	recombinant chimeric soluble enzyme	Bovine gammaherpesvirus 4	UDP + N-acetyl-beta-D-glucosaminyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,3)-N-acetyl-alpha-D-galactosaminyl-p-nitrophenol	-	?
UDP-N-acetyl-D-glucosamine + N-acetyl-beta-D-glucosaminyl-1,3-N-acetyl-alpha-D-galactosaminyl-R	enzyme shows both core 2 beta6-GalNAc-transferase activity, EC 2.4.1.102, and core 4 beta6-GalNAc-transferase activity, EC 2.4.1.148, and is termed a type M core 2 beta6-GalNAc-transferase	Bovine gammaherpesvirus 4	UDP + N-acetyl-beta-D-glucosaminyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,3)-N-acetyl-D-alpha-galactosaminyl-R	-	?
UDP-N-acetyl-D-glucosamine + N-acetyl-beta-D-glucosaminyl-1,3-N-acetyl-alpha-D-galactosaminyl-R	i.e. core 3	Bovine gammaherpesvirus 4	UDP + N-acetyl-beta-D-glucosaminyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,3)-N-acetyl-D-alpha-galactosaminyl-R	-	?

Synonyms

Synonyms	Comment	Organism
More	core 2 beta6-GalNAc-transferase, EC 2.4.1.102, exists in 2 types, type L and type M, the latter shows an additional core 4 beta6-GalNAc transferase activity	Bovine gammaherpesvirus 4

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)