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Literature summary for 2.4.1.15 extracted from
- Studies on the trehalose-phosphate synthase of Mycobacterium smegmatis: binding of heparin to the enzyme (1978), Arch. Biochem. Biophys., 186, 392-400.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| heparin | activation | Mycolicibacterium smegmatis |  |
| Triton X-100 | activation | Mycolicibacterium smegmatis | |
| Tween 80 | activation | Mycolicibacterium smegmatis | |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| (NH4)2SO4 | 1 mM | Mycolicibacterium smegmatis | |
| deoxycholate | - |
Mycolicibacterium smegmatis | |
| NaCl | 25 mM or higher | Mycolicibacterium smegmatis | |
| phosphate | 0.1 M | Mycolicibacterium smegmatis | |
| SDS | - |
Mycolicibacterium smegmatis | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 1 | - |
glucose 6-phosphate | reaction with GDPglucose | Mycolicibacterium smegmatis | |
| 1.2 | - |
glucose 6-phosphate | reaction with UDPglucose | Mycolicibacterium smegmatis | |
| 1.6 | - |
UDPglucose | - |
Mycolicibacterium smegmatis | |
| 2 | - |
glucose 6-phosphate | GDPglucose | Mycolicibacterium smegmatis | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 45000 | - |
gel filtration | Mycolicibacterium smegmatis |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mycolicibacterium smegmatis | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Mycolicibacterium smegmatis |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
- |
Mycolicibacterium smegmatis |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| UDPglucose + glucose 6-phosphate | - |
Mycolicibacterium smegmatis | trehalose 6-phosphate + UDP | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 45000, aggregation to dimer or oligomer, SDS-PAGE | Mycolicibacterium smegmatis |
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Release 2023.1 (January 2023)
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