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Literature summary for 2.4.1.152 extracted from

  • Weston, B.W.; Nair, R.P.; Larsen, R.D.; Lowe, J.B.
    Isolation of a novel human alpha (1,3)fucosyltransferase gene and molecular comparison to the human Lewis blood group alpha (1,3/1,4)fucosyltransferase gene. Syntenic, homologous, nonallelic genes encoding enzymes with distinct acceptor substrate specificities (1992), J. Biol. Chem., 267, 4152-4160.
    View publication on PubMed
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Cloned(Commentary)

Cloned (Comment) Organism
expression in COS cells Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane type II membrane protein, membrane-bound form in trans cistermae of Golgi Homo sapiens 16020
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
43008
-
 1 * 43008, calculation from nucleotide sequence Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens Q11128
-
-

Source Tissue

Source Tissue Comment Organism Textmining
leukocyte
-
 Homo sapiens
-
peripheral blood
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GDP-L-fucose + 2'-fucosyllactose 42% of the activity with Galbeta(1,4)GlcNAc Homo sapiens GDP + ?
-
 ?
GDP-L-fucose + alpha(2,3)sialyllactosamine
-
 Homo sapiens GDP + ?
-
 ?
GDP-L-fucose + Fucalpha(1,2)Galbeta(1,4)Glc
-
 Homo sapiens GDP + Fucalpha(1,2)Galbeta(1,4)(Fucalpha(1,3))Glc
-
 ?
GDP-L-fucose + Galbeta(1,3)GlcNAc i.e. lacto-N-biose I, 10% of the activity with Galbeta(1,4)GlcNAc Homo sapiens GDP + ?
-
 ?
GDP-L-fucose + Galbeta(1,4)GlcNAc
-
 Homo sapiens GDP + Galbeta(1,4)(Fucalpha(1,3))GlcNAc
-
 ?
GDP-L-fucose + Galbeta(1,4)GlcNAc i.e. N-acetyllactosamine Homo sapiens GDP + Galbeta(1,4)(Fucalpha(1,3))GlcNAc
-
 ?
GDP-L-fucose + lacto-N-biose I
-
 Homo sapiens GDP + ?
-
 ?
GDP-L-fucose + lactose 11% of the activity with Galbeta(1,4)GlcNAc Homo sapiens GDP + ?
-
 ?

Subunits

Subunits Comment Organism
monomer 1 * 43008, calculation from nucleotide sequence Homo sapiens