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Literature summary for 2.4.1.152 extracted from

  • Azuma, Y.; Kurusu, Y.; Sato, H.; Higai, K.; Matsumoto, K.
    Increased expression of Lewis X and Y antigens on the cell surface and FUT 4 mRNA during granzyme B-induced Jurkat cell apoptosis (2007), Biol. Pharm. Bull., 30, 655-660.
    View publication on PubMed
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Application

Application Comment Organism
medicine granzyme B-induced caspase 3-activation leads to up-regulation of FUT4 and FUT9 mRNA expression, which increases the surface expression of Lewis X and Y antigens Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
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Source Tissue

Source Tissue Comment Organism Textmining
JURKAT cell FUT4 mRNA is prominently expressed in Jurkat cells, a human T cell line, FUT4 and FUT9 mRNA are distinctly up-regulated in Jurkat cells 3 h and 12 h after granzyme B treatment, respectively, whereas other FUT mRNAs are not affected Homo sapiens
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JURKAT cell FUT9 mRNA is scarcely expressed in Jurkat cells, a human T cell line, FUT4 and FUT9 mRNA are distinctly up-regulated in Jurkat cells 3h and 12 h after granzyme B treatment, respectively, whereas other FUT mRNAs are not affected Homo sapiens
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Synonyms

Synonyms Comment Organism
alpha1,3-fucosyltransferase 4
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 Homo sapiens
alpha1,3-fucosyltransferase 9
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 Homo sapiens
FUT4
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 Homo sapiens
Fut9
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 Homo sapiens