Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
fucosyltransferase | - |
Homo sapiens |
FUT3 | - |
Homo sapiens |
FUT5 | - |
Homo sapiens |
FUT6 | - |
Homo sapiens |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | protein kinase R inhibitors 2-aminopurine and C16 inhibit FUT3, FUT5, and FUT6 expression. MG-132 inhibits the IMD-0354-dependent transcription of FUT5 in a dose-dependent manner | down |
Homo sapiens | protein kinase R function is essential for FUT3, FUT5, and FUT6 induction and sLex expression in Herpes simplex virus type 1-infected cells. IMD-0354, an inhibitor of the NF-kappaB-activating factor IKK-2, induces FUT transcription via a IKK-2-independent mechanism, irrespective of whether the cells are virus-infected or not | up |
General Information | Comment | Organism |
---|---|---|
physiological function | protein kinase R is the primary target for Herpes simplex virus type 1 early RNA during induction of FUT3, FUT5, and FUT6, whereby the subsequent steps in the transcriptional activation of these host genes involve a hitherto unknown IMD-0354, yet IKK-2-independent, pathway | Homo sapiens |