Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
additional information | throughout the menstrual cycle, FUT4 protein is localized to glandular and luminal epithelium in the endometrium | Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
alpha1,3 fucosyltransferase | - |
Homo sapiens |
fucosyltransferase 4 | - |
Homo sapiens |
FUT4 | - |
Homo sapiens |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | FUT4 staining is weak in proliferative and menstrual endometrium. Inductive effect of progesterone on FUT4 transcription is lost after 48 h of treatment | down |
Homo sapiens | FUT4 mRNA is significantly upregulated during the early and midsecretory stages of the menstrual cycle compared with the other menstrual phases, with maximal expression during the mid-secretory phase. In proliferative explants, progesterone significantly increases FUT4 transcription and translation after 24 h in culture. Estrogen does not have any significant effects | up |
General Information | Comment | Organism |
---|---|---|
physiological function | upregulation of selectin ligands in the endometrium at the time of implantation may be mediated, at least in part, by the regulation of FUT4 expression | Homo sapiens |