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Literature summary for 2.4.1.155 extracted from

  • Hindsgaul, O.; Kaur, K.J.; Srivastava, G.; Blaszcyk-Thurin, M.; Crawley, S.C.; Heerze, L.D.; Palcic, M.M.
    Evaluation of deoxygenated oligosaccharide acceptor analogs as specific inhibitors of glycosyltransferases (1991), J. Biol. Chem., 266, 17858-17862.
    View publication on PubMed
Search for more literature for 2.4.1.155

Inhibitors

Inhibitors Comment Organism Structure
N-Acetyl-D-glucosaminyl-1,2-alpha-6-deoxy-mannosyl-1,6-beta-D-glucosyl-O-(CH2)7-CH3 competitive Mesocricetus auratus

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Mesocricetus auratus 16020
-

Organism

Organism UniProt Comment Textmining
Mesocricetus auratus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
partial Mesocricetus auratus

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
 Mesocricetus auratus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-N-acetyl-D-glucosamine + N-acetyl-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3(6)-(N-acetyl-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6(3))-beta-D-mannosyl-1,4-N-acetyl-D-glucosaminyl-R
-
 Mesocricetus auratus UDP + N-acetyl-D-glucosaminyl-1,2-(N-acetyl-D-glucosaminyl-1,6)-1,2-alpha-D-mannosyl-1,3(6)-(N-acetyl-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6(3))-beta-D-mannosyl-1,4-N-acetyl-D-glucosaminyl-R
-
 ?
UDP-N-acetyl-D-glucosamine + N-acetyl-D-glucosaminyl-1,2-alpha-mannosyl-1,6-beta-glucosyl-O-R R: hydrophobic group, e.g. (CH2)7-CH3 Mesocricetus auratus UDP + N-acetyl-D-glucosaminyl-1,6-(N-acetyl-D-glucosaminyl-1,2)-alpha-mannosyl-1,6-beta-D-glucosyl-O-R
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Mesocricetus auratus

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.063
-
 N-Acetyl-D-glucosaminyl-1,2-alpha-6-deoxy-mannosyl-1,6-beta-D-glucosyl-O-(CH2)7-CH3
-
 Mesocricetus auratus