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Literature summary for 2.4.1.16 extracted from
- Insect chitin synthases: a review (2006), J. Comp. Physiol. B, 176, 1-15.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Drosophila melanogaster | insect development is dependent on the precisely tuned expression of chitin synthase genes. Ecdysterone has a regulatory role on CHS-1 (DmeChSB) and CHS-2 | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Anopheles gambiae | - |
- |
- |
| Drosophila melanogaster | - |
- |
- |
| Lucilia cuprina | Q9GU17 | - |
- |
| Manduca sexta | - |
- |
- |
| Spodoptera frugiperda | - |
- |
- |
| Tribolium castaneum | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| epidermis | CHS-A gene is exclusively expressed in the epidermis and related ectodermal cells such as tracheal cells | Manduca sexta | - |
| epidermis | CHS-A gene is exclusively expressed in the epidermis and related ectodermal cells such as tracheal cells | Tribolium castaneum | - |
| gut | expression of CHS-B gene is restricted to gut epithelial cells that produce chitin in the formation of the peritrophic matrix | Manduca sexta | - |
| gut | expression of CHS-B gene is restricted to gut epithelial cells that produce chitin in the formation of the peritrophic matrix | Tribolium castaneum | - |
| midgut | chitin synthase is expressed in brush border of columnar cells | Manduca sexta | - |
| trachea | CHS-A gene is exclusively expressed in the epidermis and related ectodermal cells such as tracheal cells | Manduca sexta | - |
| trachea | CHS-A gene is exclusively expressed in the epidermis and related ectodermal cells such as tracheal cells | Tribolium castaneum | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | insect development is dependent on the precisely tuned expression of chitin synthase genes. Ecdysterone has a regulatory role on CHS-1 (DmeChSB) and CHS-2 | Drosophila melanogaster | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| DmeChSB | - |
Drosophila melanogaster |
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