Literature summary for 2.4.1.16 extracted from

Sheng, W.; Yamashita, S.; Ohta, A.; Horiuchi, H.
Functional differentiation of chitin synthases in Yarrowia lipolytica (2013), Biosci. Biotechnol. Biochem., 77, 1275-1281.

Search for more literature for 2.4.1.16

Cloned(Commentary)

Cloned (Comment)	Organism
genes CHS1-4, phylogenetic tree, expression of deeltion mutants, quantitative expression analysis by RT-PCR	Yarrowia lipolytica

Protein Variants

Protein Variants	Comment	Organism
additional information	construction of deletion mutants of the 4 isozymes CHS1-CHS4, phenotypes, overview	Yarrowia lipolytica

Organism

Organism	UniProt	Comment	Textmining
Yarrowia lipolytica	-	4 isozymes, CHS1-CHS4	-
Yarrowia lipolytica CXAU1	-	4 isozymes, CHS1-CHS4	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
cell culture	growth of wild-type and enzyme mutant cells, overview	Yarrowia lipolytica	-

General Information

General Information	Comment	Organism
malfunction	the chs2DELTA mutant forms chained cells in which daughter cells are connected with mother cells and have abnormally thick septa at the bud neck. The chs4DELTA mutant shows remarkably reduced chitin content in its cell wall. The chs2DELTA, csm1DELTA, and csm2DELTA mutants are highly sensitive to chitin binding dyes, calcofluor white and Congo red, whereas the chs4DELTA mutant is resistant to calcofluor white. The lengths of the cellular long and short axes of populations of filamentous cells are decreased in the chs3DELTA mutant	Yarrowia lipolytica
additional information	chitin content in and morphological features of wild-type and enzyme mutant cells, overview	Yarrowia lipolytica
physiological function	isozymes Chs2 and Chs4 may play major roles in septum formation and cell wall chitin synthesis respectively, whereas isozymes Csm1 and Csm2 are involved in the maintenance of cell wall architecture and/or cell wall integrity. Isozyme Chs3 seems to be involved in cellular morphogenesis	Yarrowia lipolytica

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Release 2023.1 (January 2023)