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Literature summary for 2.4.1.165 extracted from

  • Wang, H.R.; Hsieh, C.Y.; Twu, Y.C.; Yu, L.C.
    Expression of the human Sda beta-1,4-N-acetylgalactosaminyltransferase II gene is dependent on the promoter methylation status (2008), Glycobiology, 18, 104-113.
    View publication on PubMed
Search for more literature for 2.4.1.165

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
UDP-N-acetyl-D-galactosamine + NeuAcalpha(2-3)Galbeta(1-4)Glc Homo sapiens responsible for the final step in the formation of the Sda/Cad antigenic epitopes, Sd(alpha) beta4GalNAcT-II mRNA transcript is drastically reduced in oncogenetic processes in gastrointestinal tissues UDP + GalNAcbeta(1-4)(NeuAcalpha(2-3))Galbeta(1-4)Glc
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Organism

Organism UniProt Comment Textmining
Homo sapiens Q8NHY0
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-

Source Tissue

Source Tissue Comment Organism Textmining
Caco-2 cell
-
 Homo sapiens
-
Colo-205 cell
-
 Homo sapiens
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HTC-116 cell
-
 Homo sapiens
-
KATO-III cell
-
 Homo sapiens
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MiaPaCa-2 cell
-
 Homo sapiens
-
SW-1417 cell
-
 Homo sapiens
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SW-48 cell
-
 Homo sapiens
-
SW-480 cell
-
 Homo sapiens
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SW-948 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-N-acetyl-D-galactosamine + NeuAcalpha(2-3)Galbeta(1-4)Glc responsible for the final step in the formation of the Sda/Cad antigenic epitopes, Sd(alpha) beta4GalNAcT-II mRNA transcript is drastically reduced in oncogenetic processes in gastrointestinal tissues Homo sapiens UDP + GalNAcbeta(1-4)(NeuAcalpha(2-3))Galbeta(1-4)Glc
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 ?

Synonyms

Synonyms Comment Organism
beta-1,4-N-acetylgalactosyltransferase II
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 Homo sapiens
beta4GalNAcT-II
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 Homo sapiens
More the short- and long-form human Sd(alpha) beta4GalNAcT-II transcripts are composed of different exon 1, exon 1S, and exon 1L Homo sapiens
Sd(alpha) beta4GalNAcT-II
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 Homo sapiens