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Literature summary for 2.4.1.17 extracted from
- Multiplicity of UDP-glucuronosyltransferases in fish. Purification and characterization of a phenol UDP-glucuronosyltransferase from the liver of a marine teleost, Pleuronectes platessa (1992), Biochem. J., 284, 417-423.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| phosphatidylcholine | required by purified preparations for optimal activity | Pleuronectes platessa |  |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| microsome | - |
Pleuronectes platessa | - |
- |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | 30 mM, activation | Pleuronectes platessa | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Pleuronectes platessa | - |
plaice | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| ammonium sulfate fractionation and affinity chromatography with UDP-hexanolamine Sepharose, several isoforms are isolated | Pleuronectes platessa |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Pleuronectes platessa | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
- |
Pleuronectes platessa |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 1-naphthol + UDP-glucuronate | - |
Pleuronectes platessa | naphth-1-yl-beta-D-glucuronide + UDP | - |
? | |
| 4-nitrophenol + UDP-glucuronate | - |
Pleuronectes platessa | 4-nitrophenyl beta-D-glucuronide + UDP | - |
? | |
| bilirubin + UDPglucuronate | no activity | Pleuronectes platessa | bilirubin monoglucuronoside + bilirubin diglucuronoside + UDP | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 52000-57000 | Pleuronectes platessa |
| ? | all values determined by SDS-PAGE | Pleuronectes platessa |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
- |
Pleuronectes platessa |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7 | - |
1-naphthol as substrate | Pleuronectes platessa |
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