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Literature summary for 2.4.1.17 extracted from

  • Fournel, S.; Gergoire, B.; Magdalou, J.; Carre, M.C.; Lafaurie, C.; Siest, G.; Caubere, P.
    Inhibition of bilirubin UDPglucuronosyltransferase activity by triphenylacetic acid and related compounds (1986), Biochim. Biophys. Acta, 883, 190-196.
    View publication on PubMed
Search for more literature for 2.4.1.17

Inhibitors

Inhibitors Comment Organism Structure
Triphenylacetic acid competitive to bilirubin Homo sapiens
Triphenylacetic acid competitive to bilirubin Rattus norvegicus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.064
-
 bilirubin 2.35 mM UDPglucuronate added Rattus norvegicus
1.06
-
 UDPglucuronate 0.125 mM bilirubin added Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
 Homo sapiens
-
-
microsome
-
 Rattus norvegicus
-
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Rattus norvegicus
-
 Wistar strain
-
Rattus norvegicus Wistar
-
 Wistar strain
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Homo sapiens
-
liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
bilirubin + UDPglucuronate
-
 Homo sapiens bilirubin monoglucuronoside + bilirubin diglucuronoside + UDP
-
 ?
bilirubin + UDPglucuronate
-
 Rattus norvegicus bilirubin monoglucuronoside + bilirubin diglucuronoside + UDP
-
 ?
bilirubin + UDPglucuronate
-
 Rattus norvegicus Wistar bilirubin monoglucuronoside + bilirubin diglucuronoside + UDP
-
 ?