Activating Compound | Comment | Organism | Structure |
---|---|---|---|
Alkyl ketones | activation | Rattus norvegicus | |
Diethylnitrosamine | 2fold to 3fold activation towards 2-aminophenol | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Lubrol 12A9 | - |
Rattus norvegicus | |
additional information | not inhibitory: N-ethylmaleimide | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Rattus norvegicus | - |
- |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | 2 to 20 mM, 30% increased activity | Rattus norvegicus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
57000 | - |
x * 57000, SDS-polyacrylamide gel electrophoresis | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
Wistar strain | - |
Rattus norvegicus Wistar | - |
Wistar strain | - |
Purification (Comment) | Organism |
---|---|
several methods including chromatofocusing, combined with anion exchange chromatography and/or affinity chromatography of UDP-hexanolamine Sepharose | Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
- |
Rattus norvegicus |
Storage Stability | Organism |
---|---|
-20°C, 20% w/v glycerol, complete loss of activity | Rattus norvegicus |
0°C, half-life 18-20 days | Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
1-naphthol + UDP-glucuronate | - |
Rattus norvegicus | naphth-1-yl-beta-D-glucuronide + UDP | - |
? | |
1-naphthol + UDP-glucuronate | - |
Rattus norvegicus Wistar | naphth-1-yl-beta-D-glucuronide + UDP | - |
? | |
4-nitrophenol + UDP-glucuronate | - |
Rattus norvegicus | 4-nitrophenyl beta-D-glucuronide + UDP | - |
? | |
4-nitrophenol + UDP-glucuronate | - |
Rattus norvegicus Wistar | 4-nitrophenyl beta-D-glucuronide + UDP | - |
? | |
morphine + UDP-glucuronate | - |
Rattus norvegicus | UDP + morphine 3,6-diglucuronide | - |
? | |
morphine + UDP-glucuronate | - |
Rattus norvegicus Wistar | UDP + morphine 3,6-diglucuronide | - |
? | |
testosterone + UDPglucuronate | - |
Rattus norvegicus | UDP + testosterone O-glucuronide | - |
? | |
testosterone + UDPglucuronate | - |
Rattus norvegicus Wistar | UDP + testosterone O-glucuronide | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 57000, SDS-polyacrylamide gel electrophoresis | Rattus norvegicus |
? | additional values for rat isozymes ranging from 51000 to 59000 | Rattus norvegicus |
? | all values determined by SDS-PAGE | Rattus norvegicus |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
inactivation in 15 min | Rattus norvegicus |