KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.014 | - |
bilirubin | apparent Km for UGT1.1 | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
endoplasmic reticulum | - |
Homo sapiens | 5783 | - |
endoplasmic reticulum | - |
Rattus norvegicus | 5783 | - |
nuclear membrane | - |
Homo sapiens | 31965 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
bilirubin + UDPglucuronate | Homo sapiens | - |
UDP + bilirubin O-glucuronide | - |
? | |
bilirubin + UDPglucuronate | Rattus norvegicus | - |
UDP + bilirubin O-glucuronide | - |
? | |
additional information | Homo sapiens | certain endogenous estrogens glucuronidated by UGT1.1 at 3-hydroxyl group of the A ring of steroids | ? | - |
? | |
additional information | Rattus norvegicus | certain endogenous estrogens glucuronidated by UGT1.1 at 3-hydroxyl group of the A ring of steroids | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
anthraflavic acid + UDPglucuronate | - |
Homo sapiens | UDP + ? | - |
? | |
anthraflavic acid + UDPglucuronate | - |
Rattus norvegicus | UDP + ? | - |
? | |
apigenin + UDPglucuronate | - |
Homo sapiens | UDP + apigenin O-glucuronide | - |
? | |
apigenin + UDPglucuronate | - |
Rattus norvegicus | UDP + apigenin O-glucuronide | - |
? | |
bilirubin + UDPglucuronate | - |
Homo sapiens | bilirubin monoglucuronoside + bilirubin diglucuronoside + UDP | - |
? | |
bilirubin + UDPglucuronate | - |
Rattus norvegicus | bilirubin monoglucuronoside + bilirubin diglucuronoside + UDP | - |
? | |
bilirubin + UDPglucuronate | - |
Homo sapiens | UDP + bilirubin O-glucuronide | - |
? | |
bilirubin + UDPglucuronate | - |
Rattus norvegicus | UDP + bilirubin O-glucuronide | - |
? | |
buprenorphine + UDPglucuronate | - |
Homo sapiens | UDP + buprenorphine O-glucuronide | - |
? | |
buprenorphine + UDPglucuronate | - |
Rattus norvegicus | UDP + buprenorphine O-glucuronide | - |
? | |
digitoxigenin + UDPglucuronate | - |
Rattus norvegicus | UDP + digitoxigenin O-glucuronide | - |
? | |
additional information | 36 substrates for HGT2B7H and HGT2B7Y. HGT2B7 glucuronidates both hydroxyl and carboxyl functions of bile acids, retinols and hydroxylated fatty acids | Homo sapiens | ? | - |
? | |
additional information | simple planar phenols, anthraquinones and opioid compounds glucuronidated by UGT1.1, aliphatic and monoterpenoid alcohols and amines not glucuronidated | Homo sapiens | ? | - |
? | |
additional information | simple planar phenols, anthraquinones and opioid compounds glucuronidated by UGT1.1, aliphatic and monoterpenoid alcohols and amines not glucuronidated | Rattus norvegicus | ? | - |
? | |
additional information | certain endogenous estrogens glucuronidated by UGT1.1 at 3-hydroxyl group of the A ring of steroids | Homo sapiens | ? | - |
? | |
additional information | certain endogenous estrogens glucuronidated by UGT1.1 at 3-hydroxyl group of the A ring of steroids | Rattus norvegicus | ? | - |
? | |
phenolphthalein + UDPglucuronate | - |
Rattus norvegicus | UDP + phenolphthalein O-glucuronide | - |
? | |
quercetin + UDPglucuronate | - |
Homo sapiens | UDP + quercetin O-glucuronide | - |
? | |
quercetin + UDPglucuronate | - |
Rattus norvegicus | UDP + quercetin O-glucuronide | - |
? |