Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.4.1.17 extracted from

  • Starlard-Davenport, A.; Lyn-Cook, B.; Radominska-Pandya, A.
    Identification of UDP-glucuronosyltransferase 1A10 in non-malignant and malignant human breast tissues (2008), Steroids, 73, 611-620.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
isozyme UGT1A10, realtime expression analysis in healthy and malignant breast tissue samples from African American and Caucasian women, overview Homo sapiens
isozyme UGT2B7, realtime expression analysis in healthy and malignant breast tissue samples from African American and Caucasian women, overview Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
UDP-D-glucuronate + 17beta-estradiol Homo sapiens
-
UDP + 17beta-estradiol 3-O-beta-D-glucuronoside
-
?
UDP-D-glucuronate + acceptor Homo sapiens
-
UDP + acceptor beta-D-glucuronoside
-
?
UDP-glucuronate + 4-hydroxy-estrone Homo sapiens glucuronidation of 4-hydroxylated estrone is significantly reduced in breast carcinomas compared to healthy UDP + ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
isozyme UGT2B7
-
Homo sapiens P36537 isozyme UGT1A10; isozyme UGT1A10
-

Source Tissue

Source Tissue Comment Organism Textmining
breast identification of isozyme UGT1A10 in non-malignant and malignant human breast tissues, UGT1A10 and UGT2B7 mRNAs are differentially expressed among healthy and malignant specimens, in African American women, UGT1A10 expression is significantly decreased in breast carcinomas in comparison to healthy, while among Caucasian women, overview Homo sapiens
-
breast UGT1A10 and UGT2B7 mRNAs are differentially expressed among healthy and malignant specimens, in African American women, UGT2B7 is significantly decreased in breast carcinomas in comparison to healthy, overview Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-D-glucuronate + 17beta-estradiol
-
Homo sapiens UDP + 17beta-estradiol 3-O-beta-D-glucuronoside
-
?
UDP-D-glucuronate + 4-hydroxy-estrone
-
Homo sapiens UDP + ?
-
?
UDP-D-glucuronate + acceptor
-
Homo sapiens UDP + acceptor beta-D-glucuronoside
-
?
UDP-glucuronate + 4-hydroxy-estrone glucuronidation of 4-hydroxylated estrone is significantly reduced in breast carcinomas compared to healthy Homo sapiens UDP + ?
-
?

Synonyms

Synonyms Comment Organism
UDP-glucuronosyltransferase 1A10
-
Homo sapiens
UGT1A10
-
Homo sapiens
UGT2B7
-
Homo sapiens