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Literature summary for 2.4.1.182 extracted from

  • Albers, U.; Tiaden, A.; Spirig, T.; Al Alam, D.; Goyert, S.M.; Gangloff, S.C.; Hilbi, H.
    Expression of Legionella pneumophila paralogous lipid A biosynthesis genes under different growth conditions (2007), Microbiology, 153, 3817-3829.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli MN7 (temperature sensitive lpxB mutant), expression of protein complements growth at 30 and 42°C Legionella pneumophila

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Legionella pneumophila involved in the biosynthetic pathway leading to 3-aminoglucosamine analogues of lipid A, responsible for cytotoxic effect on the host Acanthamoeba castellanii ?
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?

Organism

Organism UniProt Comment Textmining
Legionella pneumophila Q5WSK6 IpxB2, strain Lens; strains Philadelphia-1, Paris, and Lens, preferentially expressed in the exponential and early stationary phases, Acanthamoeba castellanii used as a host cell, construction of a insertion deletion
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Legionella pneumophila Q5WWX7 IpxB1, strain Lens; strains Philadelphia-1, Paris, and Lens, preferentially expressed in the exponential and early stationary phases, Acanthamoeba castellanii used as a host cell, construction of a insertion deletion
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Legionella pneumophila Q5X5J5 IpxB1, strain Paris; strains Philadelphia-1, Paris, and Lens, preferentially expressed in the exponential and early stationary phases, Acanthamoeba castellanii used as a host cell, construction of a insertion deletion
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information involved in the biosynthetic pathway leading to 3-aminoglucosamine analogues of lipid A, responsible for cytotoxic effect on the host Acanthamoeba castellanii Legionella pneumophila ?
-
?

Synonyms

Synonyms Comment Organism
lcsC paralogue of the lipid A disaccharide synthase lpxB, lpxB1 forms a transcriptional unit with gnnA encoding a putative UDP-GlcNAc oxidase Legionella pneumophila
lcsC/lpxB1
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Legionella pneumophila
Legionella cytotoxic suppressor C
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Legionella pneumophila
More two paralogues, lpxB1 and lpxB2 Legionella pneumophila