Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli MN7 (temperature sensitive lpxB mutant), expression of protein complements growth at 30 and 42°C | Legionella pneumophila |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Legionella pneumophila | involved in the biosynthetic pathway leading to 3-aminoglucosamine analogues of lipid A, responsible for cytotoxic effect on the host Acanthamoeba castellanii | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Legionella pneumophila | Q5WSK6 | IpxB2, strain Lens; strains Philadelphia-1, Paris, and Lens, preferentially expressed in the exponential and early stationary phases, Acanthamoeba castellanii used as a host cell, construction of a insertion deletion | - |
Legionella pneumophila | Q5WWX7 | IpxB1, strain Lens; strains Philadelphia-1, Paris, and Lens, preferentially expressed in the exponential and early stationary phases, Acanthamoeba castellanii used as a host cell, construction of a insertion deletion | - |
Legionella pneumophila | Q5X5J5 | IpxB1, strain Paris; strains Philadelphia-1, Paris, and Lens, preferentially expressed in the exponential and early stationary phases, Acanthamoeba castellanii used as a host cell, construction of a insertion deletion | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | involved in the biosynthetic pathway leading to 3-aminoglucosamine analogues of lipid A, responsible for cytotoxic effect on the host Acanthamoeba castellanii | Legionella pneumophila | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
lcsC | paralogue of the lipid A disaccharide synthase lpxB, lpxB1 forms a transcriptional unit with gnnA encoding a putative UDP-GlcNAc oxidase | Legionella pneumophila |
lcsC/lpxB1 | - |
Legionella pneumophila |
Legionella cytotoxic suppressor C | - |
Legionella pneumophila |
More | two paralogues, lpxB1 and lpxB2 | Legionella pneumophila |