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Literature summary for 2.4.1.194 extracted from

  • Chung, B.Y.; Lee, Y.; Baek, M.; Kim, J.; Wi, S.G.; Kim, J.
    Effects of low-dose gamma-irradiation on production of shikonin derivatives in callus cultures of Lithospermum erythrorhizon S (2006), Radiat. Phys. Chem., 75, 1018-1023.
No PubMed abstract available

Organism

Organism UniProt Comment Textmining
Lithospermum erythrorhizon
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the used cell line is induced from the root of Lithospermum erythrorhizon plants, cell line 622-46. A 4fold enhancement of shikonin (secondary metabolite) production is observable after a gamma radiation at the callus at 16 Gy. When the activity of p-hydroxybenzoic acid geranyltransferase is high with low activity of p-hydroxylbenzoic acid glucosyltransferase, the process of shikonin biosynthesis is boosted.
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Source Tissue

Source Tissue Comment Organism Textmining
callus
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Lithospermum erythrorhizon
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Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.002196
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the activity of p-hydroxylbenzoic acid glucosyltransferase decreases from 0.002586 micromol/min/mg to 0.002196 micromol/min/mg at 16 Gy of gamma radiation. Samples are taken two weeks after radiation. Lithospermum erythrorhizon
0.002292
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the activity of p-hydroxylbenzoic acid glucosyltransferase decreases from 0.002586 micromol/min/mg to 0.002292 micromol/min/mg at 2 Gy of gamma radiation. Samples are taken two weeks after radiation. Lithospermum erythrorhizon
0.002586
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the activity of p-hydroxylbenzoic acid glucosyltransferase decreases from 0.002586 micromol/min/mg to 0.002292 micromol/min/mg at 2 Gy of gamma radiation. Samples are taken two weeks after radiation. Lithospermum erythrorhizon

Synonyms

Synonyms Comment Organism
PHB glucosyltransferase
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Lithospermum erythrorhizon