Literature summary for 2.4.1.208 extracted from

Edman, M.; Berg, S.; Storm, P.; Wikstrom, M.; Vikstrom, S.; Ohman, A.; Wieslander, A.
Structural features of glycosyltransferases synthesizing major bilayer and nonbilayer-prone membrane lipids in Acholeplasma laidlawii and Streptococcus pneumoniae (2003), J. Biol. Chem., 278, 8420-8428.

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Activating Compound

Activating Compound	Comment	Organism	Structure
1,2-dioleoylphosphatidylglycerol	maximal activation at 30 mol%	Streptococcus pneumoniae
1,2-dioleoylphosphatidylglycerol	maximal activation at 25 mol%	Acholeplasma laidlawii
cardiolipin	very strong stimulation in the presence of 1,3-dioleoylglycerol	Acholeplasma laidlawii
additional information	not activated by cardiolipin	Streptococcus pneumoniae
phosphate	-	Acholeplasma laidlawii

Cloned(Commentary)

Cloned (Comment)	Organism
expression in Escherichia coli	Streptococcus pneumoniae
expression in Escherichia coli	Acholeplasma laidlawii

Organism

Organism	UniProt	Comment	Textmining
Acholeplasma laidlawii	-	-	-
Streptococcus pneumoniae	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
UDP-glucose + 1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol	-	Streptococcus pneumoniae	UDP + 1,2-diacyl-3-O-(alpha-D-glucopyranosyl(1->2)-O-alpha-D-glucopyranosyl)-sn-glycerol	-	?
UDP-glucose + 1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol	-	Acholeplasma laidlawii	UDP + 1,2-diacyl-3-O-(alpha-D-glucopyranosyl(1->2)-O-alpha-D-glucopyranosyl)-sn-glycerol	-	?

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Release 2023.1 (January 2023)